Studies on Pellicle and Early Dental Plaque in Relation to Periodontal Conditions
نویسنده
چکیده
..................................................................................................................................... 5 Preface........................................................................................................................................ 7 List of abbreviations................................................................................................................... 9 Introduction .............................................................................................................................. 11 Dental diseases ..................................................................................................................... 11 Dental plaque formation....................................................................................................... 12 Periodontal conditions and plaque formation....................................................................... 18 Treatment of gingivitis and periodontitis ............................................................................. 19 Hypothesis & Aims .................................................................................................................. 21 Materials & Methods................................................................................................................ 22 Saliva and plasma................................................................................................................. 22 Experimental pellicles .......................................................................................................... 22 In vivo pellicles..................................................................................................................... 22 Analysis of pellicle proteins................................................................................................. 25 Bacterial adherence .............................................................................................................. 26 Plaque sampling ................................................................................................................... 26 Microbial analysis ................................................................................................................ 26 Clinical variables.................................................................................................................. 26 Statistical analysis ................................................................................................................ 27 Results & General Discussion.................................................................................................. 28 Pellicle composition ............................................................................................................. 28 Bacterial adherence in vitro and prevalence in vivo............................................................. 32 Biofilms on upper and lower lingual surfaces...................................................................... 38 Clinical variables.................................................................................................................. 39 Consideration of methods..................................................................................................... 40 Ethical considerations .......................................................................................................... 43 Further perspectives possible relevance for periodontal disease development.................. 44 Clinical implications ............................................................................................................ 45 Concluding Remarks ................................................................................................................ 47 References ................................................................................................................................ 48 Acknowledgments.................................................................................................................... 58
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